H. HOLLANDER, M.D.; D. GREENSPAN, B.D.S.; S. STRINGARI, R.N.; J. GREENSPAN, B.D.S., Ph.D.; M. SCHIODT, B.D.S.
To the editor: Hairy leukoplakia is a distinctive lesion of the tongue that identifies persons seropositive for the acquired immunodeficiency syndrome (AIDS) virus who are at increased risk of developing frank AIDS (1, 2). The cause of this lesion is thought to be viral, with evidence of both Epstein-Barr virus replication and presence of papillomavirus antigen (3). Because papillomaviruses can be passed sexually and Epstein-Barr virus is found in proximity to other mucosal surfaces, we wondered whether hairy leukoplakia could be found on mucous membranes other than those of the mouth.
We studied 19 consecutive homosexual or bisexual men who
HOLLANDER H, GREENSPAN D, STRINGARI S, GREENSPAN J, SCHIODT M. Hairy Leukoplakia and the Acquired Immunodeficiency Syndrome. Ann Intern Med. ;104:892. doi: 10.7326/0003-4819-104-6-892_1
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Published: Ann Intern Med. 1986;104(6):892.
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