ATHAN KARTSONIS, M.D.; K. RAJENDER REDDY, M.D.; EUGENE R. SCHIFF, M.D.
To the editor: In your March issue, Seeff and coworkers (1) reported on 25 alcohol abusers who developed evidence of severe hepatic necrosis while taking acetaminophen for therapeutic purposes. Over the past 2 months, 2 young alcoholic men have been treated in our medical center for acetaminophen-induced severe hepatic necrosis. The doses ingested by each were far below those previously considered to be toxic for healthy adults.
Patient 1: A 39-year-old white alcoholic man was admitted to the Miami Veterans Administration Hospital with abdominal pain, nausea, and vomiting. He consumed 60 g of alcohol per day. Six days earlier, he
KARTSONIS A, REDDY KR, SCHIFF ER. Alcohol, Acetaminophen, and Hepatic Necrosis. Ann Intern Med. ;105:138–139. doi: 10.7326/0003-4819-105-1-138_2
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Published: Ann Intern Med. 1986;105(1):138-139.
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