AVIJIT LAHIRI, M.B., B.S. M.SC.; GIAN PIERO CARBONI, M.D.; EDWARD B. RAFTERY, M.D.
To the editor: A recent letter reported the application of nitroglycerin ointment to the buccal mucosa for relieving refractory pulmonary oedema (1). Sublingual nitroglycerin has also been used for the management of pulmonary oedema, and a comparative study of intravenous isosorbide dinitrate with furosemide has shown a better haemodynamic profile with nitrates in the management of acute heart failure occurring after infarction. Although buccal nitroglycerin ointment may have a prompt effect on left ventricular function, proper dose regulation may be difficult. Buccal-release nitroglycerin tablets which produce both rapid and sustained release of nitroglycerin are now available (2). We report here
LAHIRI A, CARBONI GP, RAFTERY EB. Buccal Nitroglycerin Tablets in Heart Failure. Ann Intern Med. ;105:141. doi: 10.7326/0003-4819-105-1-141_1
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Published: Ann Intern Med. 1986;105(1):141.
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