MATTHEW SHUSTER, M.D.; MITCHELL DUNN, M.D.
To the editor: A recent review on the use of pentamidine (1) outlines the frequent, though usually reversible, renal toxicity associated with this agent. We write to report the occurrence of gross hematuria associated with the administration of pentamidine.
A 35-year-old man with the acquired immunodeficiency syndrome presented in August 1985 with fever and massive lymphadenopathy. Lymph node biopsy samples revealed disseminated histoplasmosis. He was treated with a 2-g course of intravenous amphotericin B and placed on maintenance therapy with ketoconazole. At the end of his therapy, symptoms and adenopathy were completely resolved and renal function was normal.
SHUSTER M, DUNN M. Pentamidine and Hematuria. Ann Intern Med. ;105:146. doi: 10.7326/0003-4819-105-1-146_1
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Published: Ann Intern Med. 1986;105(1):146.
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