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Herrick first described sickle cell disease in 1910. Nobel Prize-winning research has elucidated the molecular basis of the disorder. Unfortunately, the pathogenesis of clinical manifestations and their treatment have been more resistant to understanding.
Dr. Serjeant has been a leader in trying to fill these gaps. He has critically studied sickle cell disease and its variants for 20 years in almost 3000 Jamaicans whose care he directs. Dr. Serjeant synthesizes his own observations and the work of hundreds of others (cited in 90 pages of references) in this fair, comprehensive, and highly readable book.
Beginning with a brief but thorough
Sickle Cell Disease.. Ann Intern Med. ;105:483. doi: 10.7326/0003-4819-105-3-483_1
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Published: Ann Intern Med. 1986;105(3):483.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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