VINCENT P. BUTLER JR., M.D.; THOMAS W. SMITH, M.D.
If inadvertently the doses of the Foxglove should be prescribed too largely, exhibited too rapidly, or urged to too great a length, the knowledge of a remedy to counteract its results would be a desirable thing. Such a remedy may perhaps in time be discovered.
Withering, 1785 (1)
It seemed not out of the question that non-antigenic poisons after combination with protein would call forth antibodies capable of neutralizing their toxic effect. This idea . . . would hold out hopes for practical application.
Landsteiner, 1945 (2)
WITH THE RECENT approval by the Food and Drug Administration of the use
BUTLER VP, SMITH TW. Immunologic Treatment of Digitalis Toxicity: A Tale of Two Prophecies. Ann Intern Med. ;105:613–614. doi: 10.7326/0003-4819-105-4-613
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Published: Ann Intern Med. 1986;105(4):613-614.
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