KENNETH ABREO, M.D.; JACQUE LABARRE, M.D.
To the editor: We report a syndrome of severe flank pain, hematuria, and acute renal failure that occurred after ingestion of a single dose of suprofen (Suprol, McNeil Pharmaceutical, Spring House, Pennsylvania), a recently released nonsteroidal anti-inflammatory agent.
A 27-year-old man in normal health developed severe bilateral flank pain 2 hours after ingesting 200 mg of suprofen for treatment of a headache. He did not develop gross hematuria. Physical examination showed a blood pressure of 150/94 mm Hg and bilateral flank tenderness. Urinalysis showed trace protein, 5 to 10 erythrocytes/high-power field, 5 leukocytes/high-power field, and no casts. Laboratory tests showed
ABREO K, LABARRE J. Suprofen, Acute Renal Failure, and Hematuria. Ann Intern Med. ;105:799. doi: 10.7326/0003-4819-105-5-799_2
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Published: Ann Intern Med. 1986;105(5):799.
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