VlCKl N. HOFFMAN, M.D.; OKSANA M. KORZENIOWSKI, M.D.
Increased calcitriol levels have been reported in patients who have hypercalcemia with sarcoid and other
granulomatous diseases, which suggests that calcidiol 1-alpha-hydroxylase is produced extrarenally (1, 2). Granulomatous tissue from patients with sarcoid diseases has been shown subsequently to secrete an active calcitriol-like metabolite in vitro (3, 4). Hypercalcemia recently was documented in a patient with leprosy and suppressed calcitriol levels (5). We report the case of a patient who had leprosy, hypercalcemia, and elevated calcitriol levels.
A 53-year-old East-Indian woman had emigrated to the United States 4 years before hospitalization for repair of traumatic fractures of the right proximal
HOFFMAN VN, KORZENIOWSKI OM. Leprosy, Hypercalcemia, and Elevated Serum Calcitriol Levels. Ann Intern Med. ;105:890–891. doi: 10.7326/0003-4819-105-6-890
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Published: Ann Intern Med. 1986;105(6):890-891.
Endocrine and Metabolism, Fluid and Electrolyte Disorders, Nephrology.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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