WALTER G. BARR, M.D.; ELIZABETH A. HUBBELL, R.N.; JOHN A. ROBINSON, M.D.
To the editor: Schroeder and associates (1) report two cases of patients with systemic lupus erythematosus treated with plasmapheresis and pulse cyclophosphamide. The authors state that such a therapeutic combination has not yet been applied to patients with systemic lupus erythematosus. We would like to point out our larger experience with a similar protocol that also provides some encouraging data (2).
We have treated 26 patients with persistently active systemic lupus erythematosus over a 6-month period in spite of treatment with prednisone greater than or equal to 0.5 mg/kg body weight ·d or prednisone in any dose in combination with
BARR WG, HUBBELL EA, ROBINSON JA. Plasmapheresis and Pulse Cyclophosphamide in Systemic Lupus Erythematosus. Ann Intern Med. ;108:152–153. doi: 10.7326/0003-4819-108-1-152_2
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Published: Ann Intern Med. 1988;108(1):152-153.
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