ANDREW D. LEAVITT, M.D.; ANDREW J. ZWEIFLER, M.D.
To the editor: O'Mailia and associates (1) have reported the cases of three patients who developed hypotension and myocardial ischemia secondary to sublingual nifedipine. The following case report supports the concerns raised by these authors.
A 67-year-old woman had had poorly controlled hypertension for 2 years. She had no history of rest- or exercise-related angina pectoris. She had had headache and lightheadedness, took two aspirin without relief, and went to a health clinic. At initial evaluation her vital signs included blood pressure, 260/120 mm Hg; regular pulse, 120/minute; and respiratory rate, 18/minute. She was given 10 mg of nifedipine sublingually
LEAVITT AD, ZWEIFLER AJ. Nifedipine, Hypotension, and Myocardial Injury. Ann Intern Med. ;108:305–306. doi: 10.7326/0003-4819-108-2-305
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Published: Ann Intern Med. 1988;108(2):305-306.
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