SHIGEKI SAKATA, M.D.
To the editor: Solomon and associates (1) suggest from their retrospective analysis of remission rates of Graves disease that long-term remission with antithyroid drugs depends on dietary intake of iodine. They found an inverse correlation between dietary iodine intake and remission rate, and concluded that an increased remission rate (50.7%) in patients with Graves disease is due to decreased iodine intake. They cite Azizi (2), who compared the response to methimazole in an iodine-deficient area (Tehran) and an iodine-sufficient area (Boston). Azizi concluded that initial doses needed to induce euthyroidism depends on dietary iodine intake; that is, in an iodine-deficient
SAKATA S. Remission Rates with Antithyroid Drugs. Ann Intern Med. ;108:308. doi: 10.7326/0003-4819-108-2-308_1
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Published: Ann Intern Med. 1988;108(2):308.
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