KENNETH V.I. ROLSTON, M.D.; SAUL RODRIGUEZ, M.D.; PETER W.A. MANSELL, M.D.
To the editor: Infections caused by Salmonella species occur more frequently and their manifestations, including bacteremia and dissemination, are more severe in patients with the acquired immunodeficiency syndrome (AIDS) than in those without AIDS (1). Treatment of these infections has been hampered by the emergence of strains resistant to the three main therapeutic agents (ampicillin, trimethoprim and sulfamethoxazole, and chloramphenicol) and the high incidence of adverse reactions to trimethoprim and sulfamethoxazole seen in these patients (2). Patient response is often followed by relapse on cessation of therapy (3). Isolated case reports of the successful treatment of salmonella infections with extended
ROLSTON KV, RODRIGUEZ S, MANSELL PW. Antimicrobial Therapy for Salmonella Infections in the Acquired Immunodeficiency Syndrome (AIDS). Ann Intern Med. 1988;108:309. doi: 10.7326/0003-4819-108-2-309_1
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Published: Ann Intern Med. 1988;108(2):309.
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