STEPHEN C. HADLER, M.D.
Hepatitis B vaccines have been shown to be highly effective for preventing hepatitis B for several years or more in many populations at high risk worldwide. Attention has now turned to establishing the duration of protection offered by the vaccine and the need for vaccine booster doses. In the United States, the licensed vaccine has been widely available for more than 5 years, which is the duration of reliable protection originally estimated by the vaccine's manufacturer. However, published studies have not yet shown a decline in the protection offered by the vaccine, and booster doses of vaccine have not yet
HADLER SC. Are Booster Doses of Hepatitis B Vaccine Necessary?. Ann Intern Med. ;108:457–458. doi: 10.7326/0003-4819-108-3-457
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Published: Ann Intern Med. 1988;108(3):457-458.
Gastroenterology/Hepatology, Infectious Disease, Prevention/Screening, Vaccines/Immunization, Viral Hepatitis.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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