JØRGEN THODE, M.D.; NIELS FOGH-ANDERSEN, M.D.; IB TRANSBØL, M.D., PH.D.; STIG NISTRUP HOLMEGAARD, M.D., PH.D.
To the editor: It has been suggested that nonrenal hypophosphatemia is associated with decreased sensitivity of renal tubules to parathyroid hormone in rats (1). To our knowledge there are no studies in humans supporting this concept.
A 42-year-old woman had had gastroduodenitis at gastroscopy 5 years ago. She used 10 mL of antacid three to four times daily, initially a coprecipitate of aluminum hydroxide and magnesium carbonate, later an aluminum oxide and magnesium oxide containing antacid. After treatment with antacid for 1.5 years, she developed musculoskeletal symptoms; first, pain over the loin, decreased force in the muscles of the lower
THODE J, FOGH-ANDERSEN N, TRANSBØL I, HOLMEGAARD SN. Parathyroid Hormone and Hypophosphatemia. Ann Intern Med. ;108:641–642. doi: 10.7326/0003-4819-108-4-641_3
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Published: Ann Intern Med. 1988;108(4):641-642.
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