ANGEL LOPEZ, M.D.; VICENTE JEREZ, M.D.; JESUS REBOLLO, M.D.; ANA G. LOMBARDO, M.D.; JOSE A. JULIA, M.D.
To the editor: We read with interest the article by Bismuth and colleagues (1), in which they report that "in all 17 patients, coma was present and factor V was below 20% of normal." Recently, we treated a 20-year-old patient with fulminant hepatitis associated with Amanita phalloïdes ingestion.
After charcoal hemoperfusion during the first 12 hours, the patient was treated with fresh plasma, penicillin G, thioctic acid, and parenteral nutrition (2). After 5 days, the patient was in good cardiorespiratory condition, with encephalopathy grade 2(3) and rectal bleeding. The prothrombin time (164 seconds; control, 14 seconds; 0% activity) and the
LOPEZ A, JEREZ V, REBOLLO J, LOMBARDO AG, JULIA JA. Fulminant Hepatitis and Liver Transplantation. Ann Intern Med. ;108:769. doi: 10.7326/0003-4819-108-5-769_1
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Published: Ann Intern Med. 1988;108(5):769.
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