MARIN H. KOLLEF, M.D., CPT; THOMAS IRVINE, M.D., CPT; W. HAL CRAGUN, M.D., LTC
To the editor: Gold is commonly used for treating rheumatoid arthritis. We report a case of nonbacterial thrombotic endocarditis associated with gold-induced pulmonary disease.
A 63-year-old Japanese woman was hospitalized for progressive shortness of breath. Four months before, the patient was treated with sulindac, 200 mg twice daily, for a presumptive diagnosis of rheumatoid arthritis manifested by wrist pain. She was consequently treated with four intramuscular sodium aurothiomalate injections over a 2-month period. Two weeks after the last injection, she had a diffuse urticarial skin eruption.
An arterial blood gas at admission showed a PaO2 of 25 mm Hg. A
KOLLEF MH, IRVINE T, CRAGUN WH. Nonbacterial Thrombotic Endocarditis Associated with Gold-Induced Pulmonary Disease. Ann Intern Med. ;108:903–904. doi: 10.7326/0003-4819-108-6-903_2
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Published: Ann Intern Med. 1988;108(6):903-904.
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