WALTER H. C. BURGDORF, M.D.
To the editor: I am puzzled by the report of Choksi and coworkers (1) on an unusual rash associated with a polypeptide-producing tumor of the pancreas. The authors state that the "skin lesions . . . appeared different from the migratory necrotizing erythema described with glucagonoma" and then that "skin biopsy showed focal spongiosis of the dermis . . . and no resemblance to the skin rash seen in glucagonoma."
The patient's appearance is identical to that of many patients with necrolytic migratory erythema and glucagonoma who frequently have nasolabial and periorbital erythema. A widely available article describes an almost
BURGDORF WHC. Migratory Erythema and Glucagonoma: Descriptive Nomenclature. Ann Intern Med. ;108:912–913. doi: 10.7326/0003-4819-108-6-912_2
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Published: Ann Intern Med. 1988;108(6):912-913.
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