EDWARD P. BALABAN, D.O.; RICHARD G. SHEEHAN, M.D.; PETER E. LIPSKY, M.D.; EUGENE P. FRENKEL, M.D.
We administered antithymocyte globulin to a 52-year-old man with cutaneous sclerosis (scleroderma) and severe aplastic anemia for treatment of the aplastic lesion. The use of this therapy resulted not only in marrow recovery but also in resolution of the sclerosis. This observation indicates that T lymphocytes, their products, or both, are important factors in the pathogenesis of cutaneous sclerosis. Furthermore, the success of this treatment could play a role in future investigations involving the treatment of scleroderma and scleroderma-like conditions.
BALABAN EP, SHEEHAN RG, LIPSKY PE, FRENKEL EP. Treatment of Cutaneous Sclerosis and Aplastic Anemia with Antithymocyte Globulin. Ann Intern Med. ;106:56–58. doi: 10.7326/0003-4819-106-1-56
Download citation file:
Published: Ann Intern Med. 1987;106(1):56-58.
Hematology/Oncology, Red Cell Disorders.
Results provided by:
Copyright © 2019 American College of Physicians. All Rights Reserved.
Print ISSN: 0003-4819 | Online ISSN: 1539-3704
Conditions of Use