JOHN W. WARD, M.D.; DEBORAH A. DEPPE, B.S.; SUSAN SAMSON, M.P.H.; HERBERT PERKINS, M.D.; PAUL HOLLAND, M.D.; LEONOR FERNANDO, M.D.; PAUL M. FEORINO, Ph.D; PAUL THOMPSON, M.D.; STEVEN KLEINMAN, M.D.; JAMES R. ALLEN, M.D.
Blood transfusions can transmit the human immunodeficiency virus (HIV; formerly HTLV-III/LAV), the etiologic agent of the acquired immunodeficiency syndrome (AIDS). Because serologic tests to identify HIV-infected persons were not commercially available until 1985, previous studies of HIV transmission via blood transfusion first identified transfusion-associated cases of AIDS and then, retrospectively, the respective blood donors (1-3). The blood donors implicated in HIV transmission have usually been asymptomatic at the time of donation but become viremic years after their donation (4). Thus, previous studies of transfusion-associated HIV infection could not assess the likelihood of HIV transmission from infected donors to recipients.
WARD JW, DEPPE DA, SAMSON S, PERKINS H, HOLLAND P, FERNANDO L, et al. Risk of Human Immunodeficiency Virus Infection from Blood Donors Who Later Developed the Acquired Immunodeficiency Syndrome. Ann Intern Med. ;106:61–62. doi: 10.7326/0003-4819-106-1-61
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Published: Ann Intern Med. 1987;106(1):61-62.
HIV, Infectious Disease.
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