PREM KUMAR, M.D.; JAMES E. PEARSON, M.S.; DAVID H. MARTIN, M.D.; STEPHEN H. LEECH, M.D., Ph.D.; PAUL D. BUISSERET, M.D.; HELEN C. BEZBAK, M.D.; FRANCISCO M. GONZALEZ, M.D.; JOHN R. ROYER, M.D.; H. Z. STREICHER, M.D.; W. CARL SAXINGER, Ph.D.
Human immunodeficiency virus (HIV) can be transmitted by seminal fluid and the transfusion of blood and blood products. This case report shows that organ donors may be a source for HIV infection.
Recipient: A 38-year-old woman received a renal transplant in 1982 from her HLA-identical brother. Antirejection therapy consisted of prednisone and azathioprine. During the first hospitalization, she developed fever, for which no explanation was found.
Subsequently, she had three additional prolonged hospitalizations for the evaluation of fever. On the first of these, 6 weeks after transplantation, her total leukocyte count was 2700/mm3 with 70% polymorphonuclear cells, 5% band forms,
KUMAR P, PEARSON JE, MARTIN DH, LEECH SH, BUISSERET PD, BEZBAK HC, et al. Transmission of Human Immunodeficiency Virus by Transplantation of a Renal Allograft, with Development of the Acquired Immunodeficiency Syndrome. Ann Intern Med. ;106:244–245. doi: 10.7326/0003-4819-106-2-244
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Published: Ann Intern Med. 1987;106(2):244-245.
HIV, Infectious Disease.
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