ROBERT M. CRAIG, M.D.
To the editor: In reading the article by Allman and colleagues (1) on pressure sores among hospitalized patients, I noted the association between pressure sores and hypoalbuminemia. In the discussion, the authors suggested that the hypoalbuminemia may have been due to malnutrition. Other possible causes, including hepatic disease, kidney disease, protein-losing enteropathy, and weeping of albumin from the pressure sores, were offered as possibilities. However, I believe the most important factor may have been the patients' intercurrent illnesses and the consequent diminished protein synthesis.
Very ill patients have diminished visceral protein stores, including serum proteins (2), despite increased or normal
CRAIG RM. Serum Albumin as a Nutritional Marker. Ann Intern Med. ;106:327–328. doi: 10.7326/0003-4819-106-2-327_3
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Published: Ann Intern Med. 1987;106(2):327-328.
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