ALFRED E. STILLMAN, M.D.; ROGER SCHMID, M.D.; JEFFREY B. HOWE, M.D.
To the editor: Margulis and coauthors (1) reported three patients with the acquired immunodeficiency syndrome (AIDS) and biliary tract disease resembling sclerosing cholangitis. The three patients presented with fever and diarrhea; two had right upper quadrant pain. All had alkaline phosphatase elevations ranging from 8 to 30 times the upper limit of normal. One patient had Cryptosporidium oocysts in his bile and in his surgically removed gallbladder. Another patient had cytomegalovirus inclusions in gallbladder and biliary duct epithelium and muscularis. The third patient had both cryptosporidia and cytomegalovirus mucosal inclusions at the ampulla of Vater. A fourth patient mentioned in
STILLMAN AE, SCHMID R, HOWE JB. Acquired Immunodeficiency Syndrome and Biliary Tract Disease. Ann Intern Med. ;106:634. doi: 10.7326/0003-4819-106-4-634_1
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Published: Ann Intern Med. 1987;106(4):634.
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