MORIE A. GERTZ, M.D.
To the editor: I report the case of a patient with paroxysmal cold hemoglobinuria whose disease went into remission after the initiation of danazol therapy.
A 58-year-old man developed the abrupt onset of dark red urine on 10 June 1986. He was hospitalized for evaluation of anemia. His hemoglobin level consistently fell below 7 g/dL and over the next 30 days he required a total of 28 units of packed erythrocytes. A 1-month trial of prednisone at 1 mg/kg body weight · d did not reduce his transfusion requirement and was discontinued. Physical examination was normal except for pallor and
GERTZ MA. Possible Response of Paroxysmal Cold Hemoglobinuria to Danazol. Ann Intern Med. ;106:635. doi: 10.7326/0003-4819-106-4-635_1
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Published: Ann Intern Med. 1987;106(4):635.
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