BETTY S. ROOF, M.D.
To the editor: In their recent article, Ettinger and colleagues (1) state that 9.0% of untreated women with postmenopausal osteoporosis and 10.5% of women given calcium supplements had mean decrease in spinal trabecular mineral content (determined by quantitative computed tomography) during the 2-year study. In women given conjugated estrogens, 0.3 mg/d, with calcium supplements, there was an increase in mineral content of 2.3% during this period. The authors contrast these findings with those from their earlier study (2) in which treatment with conjugated estrogens, 0.15 to 0.45 mg/d, did not prevent bone loss in women who had had oophorectomy, whereas
ROOF BS. Treatment of Postmenopausal Osteoporosis. Ann Intern Med. ;106:780. doi: 10.7326/0003-4819-106-5-780_1
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Published: Ann Intern Med. 1987;106(5):780.
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