To the editor: In the article by Aronson and Bor (1) on the performance of the blood culture as a diagnostic test, emphasis is placed on the importance of culturing at least 10 mL of blood for optimal isolation of organisms. Previous reports comparing 5 mL with 2 mL, 10 mL and 15 mL with 5 mL, and most recently 30 mL with 15 mL, have all shown a greater yield of positive isolates when larger volumes of blood are cultured (2). The authors also correctly state that the optimal blood-to-broth ratio is between 1:5 and 1:10 when liquoid (sodium
WILKINS E. Liquoid in Blood Cultures. Ann Intern Med. ;106:912. doi: 10.7326/0003-4819-106-6-912_2
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Published: Ann Intern Med. 1987;106(6):912.
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