MARIN H. KOLLEF, M.D.
To the editor: Ammonium hydroxide is a colorless, highly soluble, extremely irritant alkaline gas that is widely used in private and industrial settings (1). The major toxicity occurs secondary to acute exposure with severe laryngeal and pulmonary edema (2). The effects of chronic low level exposure are unknown. I recently evaluated a patient with chronic exposure who presented with possible ocular, upper airway, and pulmonary manifestations.
A 54-year-old man had a history of mild hypertension and adult onset diabetes mellitus, as well as a 20 pack-year history of smoking. He had no cardiopulmonary symptoms. He was referred for evaluation of
KOLLEF MH. Chronic Ammonium Hydroxide Exposure. Ann Intern Med. ;107:118. doi: 10.7326/0003-4819-107-1-118_1
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Published: Ann Intern Med. 1987;107(1):118.
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