BENJAMIN A. LIPSKY, M.D.; JAN V. HIRSCHMANN, M.D.
To the editor: Anthonisen and coworkers' (1) article on antibiotic treatment for exacerbations of chronic obstructive pulmonary disease was enlightening. The study's unique design, careful performance, and thoughtful discussion are exemplary, especially compared with previous investigations. We do, however have a few specific questions.
The authors state that an approximately equal percentage of patients receiving antibiotics and placebo also were treated with corticosteroids, but they do not specify the distribution of prednisone recipients among the three types of exacerbations. In type 1 exacerbations (where antibiotics seemed most beneficial) a disproportionately greater use of steroids in patients receiving antibiotics compared with
LIPSKY BA, HIRSCHMANN JV. Antibiotic Therapy and Chronic Obstructive Lung Disease. Ann Intern Med. ;107:254. doi: 10.7326/0003-4819-107-2-254
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Published: Ann Intern Med. 1987;107(2):254.
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