L. J. COUDERC, M.D.; J. P. CLAUVEL, M.D.
To the editor: Human immunodeficiency virus (HIV) infection has been associated with a broad clinical spectrum of diseases (1). We report the onset of transient gynecomastia in two HIV-infected patients.
Patient 1, a 36-year-old intravenous drug user and homosexual man, developed enlargement of his right mammary gland. Physical examination 1 year later showed bilateral, painless gynecomastia. Serum antibodies to HIV were detected by enzyme-linked immunosorbent assay (ELISA) technique and Western blot. The numbers of T-cells were within normal limits (T3, 1700/mm3; T4, l000/mm3; and T8, 500/mm3) and the T4/T8 ratio was 2. Gynecomastia spontaneously resolved 6 months later.
COUDERC LJ, CLAUVEL JP. HIV-Infection-Induced Gynecomastia. Ann Intern Med. ;107:257. doi: 10.7326/0003-4819-107-2-257_1
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Published: Ann Intern Med. 1987;107(2):257.
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