JOEL TSEVAT, M.D.; GARY N. GROSS, M.D.; GRAEME P. DOWLING, M.D.
To the editor: Allergy to sulfite preservatives is common among asthmatics—as many as 5% to 11% are sulfite-sensitive (1, 2). Fourteen deaths have been precipitated by the ingestion of sulfite-containing foods (1). We report the case of an asthmatic who had a fatal anaphylactic reaction after drinking a glass of wine high in sulfite content. We believe this is the first report of a fatal anaphylactic reaction to wine.
A 33-year-old man first developed asthma in 1976 at age 24. He soon required chronic steroid therapy (prednisone, 20 mg/d), theophylline (1200 mg/d), inhaled beta-agonists, and cromolyn sodium. Despite the severity
TSEVAT J, GROSS GN, DOWLING GP. Fatal Asthma After Ingestion of Sulfite-Containing Wine. Ann Intern Med. ;107:263. doi: 10.7326/0003-4819-107-2-263_2
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Published: Ann Intern Med. 1987;107(2):263.
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