DAVID E. FISHER, M.D., Ph.D.
To the editor:
A leukopenic drug allergy occurred in a patient with longstanding refractory eczema. There was subsequently a striking remission in the eczema disease activity.
A 50-year-old white woman had fevers, arthralgias, myalgias, and a new maculopapular rash. She had more than a 3-year history of unremitting eczematous dermatitis over the extensor surfaces of all four extremities refractory to several topical therapies. She was begun on phenytoin, 300 mg/d, for severe migraine headaches for which more conventional therapies had failed, 7 days before admission. Five days later the patient noted onset of malaise, arthralgias, myalgias, worsened headaches, and fevers
DAVID E. FISHER. Phenytoin, Leukopenia, and Remission of Eczema. Ann Intern Med. 1987;107:263–264. doi: 10.7326/0003-4819-107-2-263_3
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Published: Ann Intern Med. 1987;107(2):263-264.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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