SAMUEL STROBER, M.D.; M. CARMEN FARINAS, M.D., Ph.D.; ELIZABETH H. FIELD, M.D.; JOSE J. SOLOVERA, M.D.; BRYCE A. KIBERD, M.D.; BRYAN D. MYERS, M.D.; RICHARD T. HOPPE, M.D.
In a previous study (1), we treated 10 patients with diffuse lupus nephritis, a moderate to high chronicity index on the renal biopsy, and nephrotic syndrome with total lymphoid irradiation as an alternative to cytotoxic drug therapy (2-7). Before total lymphoid irradiation, lupus renal disease activity was not controlled after 3 months of prednisone (0.5 mg/kg body weight · d or greater) alone or in combination with azathioprine, or recurred when the prednisone dosage was tapered below 0.5 mg/kg body weight · d (1). This report extends the follow-up of the 10 patients with lupus nephritis up to 6 years,
STROBER S, FARINAS MC, FIELD EH, SOLOVERA JJ, KIBERD BA, MYERS BD, et al. Lupus Nephritis After Total Lymphoid Irradiation: Persistent Improvement and Reduction of Steroid Therapy. Ann Intern Med. ;107:689–690. doi: 10.7326/0003-4819-107-5-689
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Published: Ann Intern Med. 1987;107(5):689-690.
Autoimmune Kidney Disease, Lupus Erythematosus, Nephrology, Rheumatology.
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