LARRY M. BUSH, M.D.; JEROME A. BOSCIA, M.D.
Neisseria Gonorrhoeae usually causes a localized mucosal infection. However, in 1% to 3% of cases, the organism disseminates and produces various clinical syndromes (1). Two of the commoner manifestations of disseminated gonococcal infection are septic arthritis and tenosynovitis (2). In sexually active young persons, disseminated gonococcal infection is the most frequent cause of septic arthritis (2). In most studies on disseminated gonococcal infection, only strains of N. gonorrhoeae that are very sensitive to penicillin are reported to produce this syndrome (3, 4). The association between clinical virulence of the organism and dissemination may be linked to low antibiotic resistance in
BUSH LM, BOSCIA JA. Disseminated Multiple Antibiotic-Resistant Gonococcal Infection: Needed Changes in Antimicrobial Therapy. Ann Intern Med. ;107:692–693. doi: 10.7326/0003-4819-107-5-692
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Published: Ann Intern Med. 1987;107(5):692-693.
Infectious Disease, Sexually Transmitted Infections.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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