Daniel Havlichek, MD
To the Editor: Recurrent Pneumocystis carinii pneumonia occurs frequently in patients with the acquired immunodeficiency syndrome (AIDS). Because these patients often have reactions to trimethoprim-sulfamethoxazole or pentamidine or both (1), these patients sometimes need treatment with a medication to which they are sensitive. Two small, independent studies (2, 3) have shown that aerosolized pentamidine may be an effective therapy for P. carinii pneumonia in patients with AIDS. Both aerosol regimens were associated with equivalent or fewer toxicities when compared with systemic therapy. In these studies, no patient had known pentamidine intolerance. We report the safe use of aerosolized pentamidine in
Havlichek D. Aerosolized Pentamidine Therapy. Ann Intern Med. ;109:167–168. doi: 10.7326/0003-4819-109-2-167
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Published: Ann Intern Med. 1988;109(2):167-168.
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