Ronald G. Nahass, MD; David Alcid, MD; David J. Gocke, MD
To the Editor: We agree with Dr. Whitley (1) that, despite the lack of controlled trials on the use of ganciclovir in cytomegalovirus chorioretinitis, data suggest it is beneficial. We report a case that shows the need for placebo-controlled trials for cytomegalovirus-related disease.
A 30-year-old male intravenous drug user with group 4 human immunodeficiency virus type 1 (HIV-1) infection had multiple scotomata that had developed over a 2-week period. Funduscopic examination showed bilateral perivascular retinal hemorrhages and pale yellow plaques. Serum IgG titer for cytomegalovirus was positive at 1:32 dilution. A urine culture for cytomegalovirus was also positive. Azidothymidine treatment
Nahass RG, Alcid D, Gocke DJ. Spontaneous Remission of Retinitis in a Case of Infection with Human Immunodeficiency Virus Type 1 (HIV-1). Ann Intern Med. ;109:168. doi: 10.7326/0003-4819-109-2-168_1
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Published: Ann Intern Med. 1988;109(2):168.
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