Bruce Freundlich, MD; Dave Makover, MD; Gerd G. Maul, PhD
The association of malignancy with lupus-like syndromes is rare, and the relation between these two processes is uncertain. A 71-year-old woman who presented with serositis, Raynaud phenomenon, and positive results on an antinuclear antibody test was initially thought to have systemic lupus erythematosus but was found to have ovarian adenocarcinoma. A unique sparsely speckled antinuclear antibody pattern was seen. The patient's sera reacted to novel antigens with six bands of 100, 80-78, 48, and 17 kD on Western blots not typical of reactivity for sera from patients with systemic lupus erythematosus.
Bruce Freundlich, Dave Makover, Gerd G. Maul. A Novel Antinuclear Antibody Associated with a Lupus-like Paraneoplastic Syndrome. Ann Intern Med. 1988;109:295–297. doi: 10.7326/0003-4819-109-4-295
Download citation file:
Published: Ann Intern Med. 1988;109(4):295-297.
Lupus Erythematosus, Rheumatology.
Results provided by:
Copyright © 2017 American College of Physicians. All Rights Reserved.
Print ISSN: 0003-4819 | Online ISSN: 1539-3704
Conditions of Use