Abe M. Macher, MD; Ronald Neafie, MS; Peter Angritt, MC; Sylvana M. Tuur, MD
To The Editor: In 1985, Ledford and colleagues (1) reported the first case of a patient with the acquired immunodeficiency syndrome (AIDS) with myositis secondary to a microsporidial infection. At clinical presentation in 1983, the patient was a cachectic, 20-year-old black man residing in Florida. He had progressive, generalized muscle weakness with contractures; generalized nontender lymphadenopathy; testicular atrophy; gynecomastia; sinusitis; fever; and a weight loss of 18 kg. Laboratory studies showed anemia, lymphocytopenia, cutaneous anergy, decreased in-vitro lymphocyte blast transformation, and a T-helper/T-suppressor cell ratio of 0.4. Serologic titers to cytomegalovirus, Epstein-Barr virus, hepatitis B virus, and syphilis were all
Macher AM, Neafie R, Angritt P, Tuur SM. Microsporidial Myositis and The Acquired Immunodeficiency Syndrome (AIDS): A Four-Year Follow-Up. Ann Intern Med. ;109:343. doi: 10.7326/0003-4819-109-4-343_1
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Published: Ann Intern Med. 1988;109(4):343.
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