Marvin A. Sackner, MD; Bruce P. Krieger, MD
To the Editor: Murciano and colleagues (1) showed that tracheal occlusion pressure (P0.1) provided a better predictive index for successful extubation than classic weaning criteria in patients with exacerbation of chronic obstructive pulmonary disease. The authors also correlated P0.1 with electromyographic evidence of diaphragmatic fatigue and concluded that P0.1 provided "a valid and simple index to assess the likelihood of respiratory muscle fatigue."
The authors reported that respiratory frequency (f) significantly decreased (P < 0.005) in 11 patients successfully extubated (group 1) in contrast to the chronic elevations that occurred in five patients who later needed to have mechanical ventilatory
Sackner MA, Krieger BP. Respiratory Muscle Fatigue. Ann Intern Med. ;109:758. doi: 10.7326/0003-4819-109-9-758_1
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Published: Ann Intern Med. 1988;109(9):758.
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