Sam Schulman; Hans Johnsson; Sven Blomqvist
To the Editor: Goldsmith and colleagues (1) reported five cases of primary pulmonary hypertension in hemophiliacs infected with human immunodeficiency virus (HIV). We report another case, in which clinical improvement occurred.
A 50-year-old man with classic hemophilia (factor VIII, <0.01 U/mL) was diagnosed as having pulmonary hypertension in September 1987. He had received treatment with lyophilized factor concentrates of low purity between 1961 and 1977, and concentrates of intermediate purity thereafter. Since 1977, he received regular self-administered prophylaxis (average annual usage, 95 000 units). The patient had severe hemophilic arthropathy. Antibodies to hepatitis B surface antigen were present since at
Schulman S, Johnsson H, Blomqvist S. Pulmonary Hypertension in Hemophilia. Ann Intern Med. ;109:759–760. doi: 10.7326/0003-4819-109-9-759
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Published: Ann Intern Med. 1988;109(9):759-760.
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