S. J. O. Veldhuyzen van Zanten, MD, MPH; J. Goldie; R.H. Riddell, MD; Richard H. Hunt, MD
To the Editor: We have difficulty with the conclusions reached by Perez-Perez and colleagues (1) on the use of Campylobacter pylori antibodies to determine the prevalence of C. pylori infection in healthy persons. The results of their IgG and IgA enzyme-linked immunosorbent assay (ELISA) tests have been used as another way to diagnose infection with C. pylori,but the current accepted "gold standard" for detecting this organism is the histologic examination or culture of endoscopically obtained gastric biopsy specimens. The 13C-urea and 14C-urea breath tests are other tests that can be used as a gold standard for detecting C. pylori; the
Veldhuyzen van Zanten SJO, Goldie J, Riddell R, Hunt RH. Campylobacter pylori Infection. Ann Intern Med. ;109:925–926. doi: 10.7326/0003-4819-109-11-925
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Published: Ann Intern Med. 1988;109(11):925-926.
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