Anne Francois, MD; Marc Freund, MD; Fernand Daffos, MD; Philippe Remy, MD; Martine Aiach, MD; Christian Jacquot, MD
To the Editor: Combined therapy with prednisone and low doses of aspirin has been reported to reduce the risk for fetal loss in women with the lupus anticoagulant (1, 2). We report a case in which a woman with the lupus anticoagulant had had three successive fetal losses while receiving this combined therapy. The outcome of a fourth pregnancy was favorable when she was given high-dose intravenous polyvalent immunoglobulin therapy.
A 24-year-old woman had episodes of deep venous thrombosis and pulmonary embolism when she was 18, 19, and 22 years of age. She was found to have the lupus anticoagulant
Francois A, Freund M, Daffos F, Remy P, Aiach M, Jacquot C. Repeated Fetal Losses and the Lupus Anticoagulant. Ann Intern Med. ;109:993–994. doi: 10.7326/0003-4819-109-12-993
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Published: Ann Intern Med. 1988;109(12):993-994.
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