Anthony L. Komaroff, MD; Stephen E. Straus, MD; Nelson M. Gantz, MD; James F. Jones, MD
To the Editor: Manu and colleagues (1) recently reported that a large proportion of self-selected patients with chronic fatigue have various psychiatric conditions, as determined by the application of a structured interview, the Diagnostic Interview Schedule (DIS), and that only a few patients had well-recognized organic illnesses.
We agree that primary psychiatric disease is common in patients with fatigue and that only an occasional patient seeking medical care for chronic fatigue has a well-recognized organic illness, such as an occult malignancy. We believe that there is another disorder, the chronic fatigue syndrome, that is also likely to be an organic
Komaroff AL, Straus SE, Gantz NM, Jones JF. The Chronic Fatigue Syndrome. Ann Intern Med. ;110:407–408. doi: 10.7326/0003-4819-110-5-407
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Published: Ann Intern Med. 1989;110(5):407-408.
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