Ann Parke, MBBS; Donald Maier, MD; Daniel Wilson, BA; John Andreoli, MD; Mark Ballow, MD
To the Editor: In their letter ( 1 ) on the use of intravenous immunoglobulin therapy (IVIG) in pregnant women with antiphospholipid antibodies and a history of fetal loss, Francois and colleagues suggest that IVIG may be the safest therapy to use in such women. From our experience with a young woman with the primary antiphospholipid antibody syndrome, we agree with their recommendation.
In a 29-year-old white woman who previously had five spontaneous abortions, a full gynecologic examination failed to show any cause for her recurrent abortions. Tests for autoantibodies, including antiphospholipid (APL) antibodies, indicated the presence of numerous autoantibodies,
Parke A, Maier D, Wilson D, Andreoli J, Ballow M. Intravenous Gamma-Globulin, Antiphospholipid Antibodies, and Pregnancy. Ann Intern Med. ;110:495–496. doi: 10.7326/0003-4819-110-6-495_2
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Published: Ann Intern Med. 1989;110(6):495-496.
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