Martin J. Weiner, MD
To the Editor: In recent years methotrexate has been used with varying degrees of success in a host of conditions other than neoplastic disorders. Severe psoriasis, primary biliary cirrhosis (1), sclerosing cholangitis (2), corticosteroid dependent asthma (3), and rheumatoid arthritis (4) are among the diverse conditions treated with some success with methotrexate.
To my knowledge this is the first report describing probable benefit of methotrexate in longstanding acute and chronically debilitating urticaria of unknown cause which had become corticosteroid unresponsive over a 24-year period.
A 48-year-old, otherwise healthy male attorney, presented in April 1988 with a 24-year history of urticaria
Weiner MJ. Methotrexate in Corticosteroid-Resistant Urticaria. Ann Intern Med. 1989;110:848. doi: 10.7326/0003-4819-110-10-848_1
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Published: Ann Intern Med. 1989;110(10):848.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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