David A. Tate, MD; Gregory J. Dehmer, MD
A survey of recent medical literature might suggest that the major challenges in the field of coronary thrombolysis have been met. Several large, randomized trials have now established that thrombolytic therapy not only restores coronary patency (1), but also that this restoration of patency is associated with improved left ventricular function (2) and reduced mortality (3-7). In this issue, however, Lee and colleagues (8) document in a large study what many observers and several smaller studies have previously suggested-that is, using current clinical practices only a small fraction of patients with myocardial infarction are likely to be treated with thrombolytic
Tate DA, Dehmer GJ. New Challenges for Thrombolytic Therapy. Ann Intern Med. 1989;110:953–955. doi: 10.7326/0003-4819-110-12-953
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Published: Ann Intern Med. 1989;110(12):953-955.
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