Mario C. Raviglione, MD; Peter Mariuz, MD; Jeffrey Sugar, MD; Michael P. Mullen, MD
To the Editor: Extrapulmonary pneumocystosis has recently been reported in patients with the acquired immunodeficiency syndrome (AIDS) (1-5). This condition appears to be rare despite the high frequency of Pneumocystis carinii pneumonia, still the commonest opportunistic infection associated with AIDS. However, the use of inhaled pentamidine for prophylaxis of P. carinii pneumonia may predispose to extrapulmonary pneumocystosis (5). Inhaled pentamidine is delivered directly to the alveoli where P. carinii usually reside but is unable to reach distant sites. We recently treated two patients who developed extrapulmonary pneumocystosis while receiving inhaled pentamidine for prophylaxis of P. carinii pneumonia.
A 34-year-old homosexual
Raviglione MC, Mariuz P, Sugar J, Mullen MP. Extrapulmonary Pneumocystis Infection. Ann Intern Med. ;111:339–340. doi: 10.7326/0003-4819-111-4-339
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Published: Ann Intern Med. 1989;111(4):339-340.
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