Richard T. Davey Jr, MD; David Margolis, MD; David Kleiner, MD; Lawrence Deyton, MD; William Travis, MD
Pneumocystis carinii pneumonia occurs with unusually high frequency in patients with human immunodeficiency virus (HIV) infection and contributes substantially to the morbidity and mortality associated with the acquired immunodeficiency syndrome (AIDS). A feature of infection with this pathogen is that disease is almost always confined to the lung, with extrapulmonary spread rarely reported. As a result, recent strategies to prevent pneumocystis infection without causing systemic toxicity have focused on aerosolized drug delivery to the lungs (1).
In 1982, a 26-year-old heterosexual male developed stage III testicular germ cell malignancy that was treated with orchiectomy and combination chemotherapy. He did well
Davey RT, Margolis D, Kleiner D, Deyton L, Travis W. Digital Necrosis and Disseminated Pneumocystis carinii Infection after Aerosolized Pentamidine Prophylaxis. Ann Intern Med. ;111:681–682. doi: 10.7326/0003-4819-111-8-681
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Published: Ann Intern Med. 1989;111(8):681-682.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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