Leslie Grammer, MD
To the Editor: I am writing in response to the article by Yoshizawa and colleagues (1) on hypersensitivity pneumonitis and toluene diisocyanate. Two areas deserve comment. First, the authors state that the worker developed hypersensitivity pneumonitis 1 week after he began working with paint materials containing toluene diisocyanate. In the absence of previous exposure, hypersensitivity pneumonitis does not develop after 1 week of exposure. Second, it does not appear that the worker's exposure was "continuous" as the title of the article suggests. His exposure was probably almost nil if he was wearing the "preventive oxygen-powered mask." His subsequent absence of
Grammer L. Hypersensitivity Pneumonitis and Toluene Diisocyanate. Ann Intern Med. ;111:690–691. doi: 10.7326/0003-4819-111-8-690_2
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Published: Ann Intern Med. 1989;111(8):690-691.
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