Allan D. Eisemann, MD; Nancy J. Becker, MD; Philip B. Miner Jr., MD; Jon Fleming, MD
To the Editor: Gold treatment of rheumatic diseases is frequently curtailed by treatment-limiting skin rash, mucositis, proteinuria, and diarrhea. Less frequent but more toxic side effects include gold-induced hepatitis, "gold lung," neutropenia, and peripheral neuropathy. We describe two cases of pancreatitis associated with gold treatment.
A 44-year-old white woman with rheumatoid arthritis developed mild fever and upper abdominal pain associated with nausea, vomiting, fever (102.2°F) and diminished bowel sounds 5 days after her fifth injection of gold (total dose, 160 mg). By day 4, amylase peaked at 520 IU/L (normal, 5 to 90 IU/L) and lipase was greater than 90
Eisemann AD, Becker NJ, Miner PB, Fleming J. Pancreatitis and Gold Treatment of Rheumatoid Arthritis. Ann Intern Med. 1989;111:860–861. doi: 10.7326/0003-4819-111-10-860_2
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Published: Ann Intern Med. 1989;111(10):860-861.
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