Jorge P. Ferrer, MD; Irene Halperin, MD; Josep Palou, MD
To the Editor: Gagel and colleagues (1) recently described an association of hereditary cutaneous amyloidosis with multiple endocrine neoplasia type 2a. We recently encountered an identical skin lesion in a case of hereditary medullary thyroid carcinoma that we believe confirms the hypothesis that the simultaneous appearance of these rare diseases is not a mere coincidence.
A 30-year-old woman was evaluated at our clinic in the setting of a familial-medullary-thyroid-carcinoma screening program. She was asymptomatic except for slight interscapular pruritus of several years duration. Physical examination revealed a right thyroid nodule, 0.8 cm in diameter, and a 2-by-3-cm papular and pigmented
Ferrer JP, Halperin I, Palou J. Cutaneous Lichen Amyloidosis and Familial Medullary Thyroid Carcinoma. Ann Intern Med. ;112:551–552. doi: 10.7326/0003-4819-112-7-551
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Published: Ann Intern Med. 1990;112(7):551-552.
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