Michael F. Tenholder, MD; Gregory L. Becker, MD; Manuel I. Cervoni, MD
To the Editor: We have identified bronchiolitis obliterans with organizing pneumonia as a cause of refractory hypoxemia, infiltrates, and relentless fever in a patient with the myelodysplastic syndrome. A 58-year-old white man with a 40-pack-year smoking history presented with a 6-week history of fever, productive cough, dyspnea, and a weight loss of 4 kg. He also had pancytopenia. The total leukocyte count was 2700/mm3; the hemoglobin, 10.0 g/dL; and the platelet count, 73 x 103/ mm3. A bone marrow biopsy specimen showed refractory anemia with excess blasts—a myelodysplastic syndrome. Physical examination showed the following: blood pressure, 125/65 mm Hg; pulse
Tenholder MF, Becker GL, Cervoni MI. The Myelodysplastic Syndrome and Bronchiolitis Obliterans. Ann Intern Med. ;112:714–715. doi: 10.7326/0003-4819-112-9-714
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Published: Ann Intern Med. 1990;112(9):714-715.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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